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Ligand Recognition by E- and P-Selectin: Chemoenzymatic Synthesis and Inhibitory Activity of Bivalent Sialyl Lewis x Derivatives and Sialyl Lewis x Carboxylic Acids

✍ Scribed by Wittmann, Valentin; Takayama, Shuichi; Gong, Ke Wei; Weitz-Schmidt, Gabriele; Wong, Chi-Huey


Book ID
126068466
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
98 KB
Volume
63
Category
Article
ISSN
0022-3263

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Chemoenzymatic Synthesis and Fluorescent
✍ Valentin Wittmann; Arun K. Datta; Kathryn M. Koeller; Chi-Huey Wong πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 249 KB πŸ‘ 2 views

Sialyl Lewis x (sLe x ) derivatives conjugated to readily visualized molecular labels are useful chemical probes to study selectin Β± carbohydrate interactions. Localization of the selectins on the surface of leukocytes and activated endothelial cells can be detected through fluorescence of bound sel