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Ligand-mediated retargeting of recombinant adenovirus for gene transfer in vivo

✍ Scribed by Thoma, C; Wieland, S; Moradpour, D; von Weizsäcker, F; Offensperger, S; Madon, J; Blum, H E; Offensperger, W-B

Book ID
110038690
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
411 KB
Volume
7
Category
Article
ISSN
0969-7128

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Adenovirus-mediated gene transfer in olf
Adenovirus-mediated gene transfer in olfactory neuronsin vivo
✍ Zhao, Haiqing ;Otaki, Joji M. ;Firestein, Stuart 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 949 KB

We used recombinant adenoviruses as a means of expressing exogenous genes in olfactory neurons in vivo. A replication incompetent adenovirus (type 5, Ad5) carrying the reporter gene lacZ, which codes for the enzyme 8-galactosidase (,&Gal), was applied in solution to the olfactory epithelia of rats.