Asymmetric resins containing optically active bi-or tridentate a-amino acids as fixed ligands coordinated with Cu 2+, NiZ+ or other transition metal ions can be used for the ligand-exchange chromatography of racemic a-amino acids. The degree of resolution of enantiomers depends both on the nature of
Ligand exchange amino acid analysis: Resolution of some amino sugars and cysteine derivatives
β Scribed by Fred W. Wagner; Sara L. Shepherd
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- English
- Weight
- 501 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0003-2697
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A series of three new quadridentate ligands was synthesized by reaction of the haloacetylated amino acid esters L- BrAc-Phe-OMe (4a), L-BrAc-Lys(Z)-OMe (4b), and ClAc-Gly-OEt (4c), respectively, with bis(picolyl)amine (bpa, 5). The obtained products L-bpaAc-Phe-OMe (3a), L-bpaAc-Lys(Z)-OMe (3b), and