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Ligand Binding to Integrins

✍ Scribed by Plow, E. F.; Haas, T. A.; Zhang, L.; Loftus, J.; Smith, J. W.


Book ID
126306553
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2000
Tongue
English
Weight
700 KB
Volume
275
Category
Article
ISSN
0021-9258

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Integrins are a family of transmembrane proteins composed of heterodimers of ␣ and ␀ subunits. With their extracellular domain they bind extracellular matrix proteins or other cell surface molecules, and their cytoplasmic domain binds to cytoskeletal and signaling proteins. Thus, they are in an idea