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Ligand binding: functional site location, similarity and docking

✍ Scribed by Stephen J Campbell; Nicola D Gold; Richard M Jackson; David R Westhead

Book ID
114314628
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
147 KB
Volume
13
Category
Article
ISSN
0959-440X

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## Abstract Present docking methodologies simulate only one single ligand at a time during docking process. In reality, the molecular recognition process always involves multiple molecular species. Typical protein–ligand interactions are, for example, substrate and cofactor in catalytic cycle; meta