Ligand-binding and autoradiographic studies of GABA-receptors in tissue culture
โ Scribed by DeFeudis, F.V.
- Book ID
- 123463088
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 311 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0306-3623
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๐ SIMILAR VOLUMES
Autoradiographic studies were conducted on the binding of 3H-GABA and 3H-muscimol in cultures of rat cerebellum. Binding sites for both substances were observed on many cerebellar neurones, such as Purkinje cells and interneurones, but not on glial cells. Binding of 3H-GABA and 3H-muscimol was inhib
The cellular localization of GABA-binding sites was studied in explant cultures of rat cerebellum, brain stem and spinal cord by means of autoradiography. Labelling of GABAB-sites was done with 3H(-)baclofen or 3H-GABA in presence of unlabelled bicuculline. Binding sites for these radio-ligands were