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Autoradiographic localization of3H-GABA and3H-muscimol binding in rat cerebellar cultures

✍ Scribed by E. Hösli; L. Hösli

Publisher
Springer-Verlag
Year
1980
Tongue
English
Weight
703 KB
Volume
38
Category
Article
ISSN
0014-4819

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✦ Synopsis

Autoradiographic studies were conducted on the binding of 3H-GABA and 3H-muscimol in cultures of rat cerebellum. Binding sites for both substances were observed on many cerebellar neurones, such as Purkinje cells and interneurones, but not on glial cells. Binding of 3H-GABA and 3H-muscimol was inhibited by unlabelled GABA and by the GABA antagonist bicuculline.

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