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Ligand-Accelerated Cu-Catalyzed Azide−Alkyne Cycloaddition: A Mechanistic Report

✍ Scribed by Rodionov, Valentin O.; Presolski, Stanislav I.; Díaz Díaz, David; Fokin, Valery V.; Finn, M. G.


Book ID
111865598
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
256 KB
Volume
129
Category
Article
ISSN
0002-7863

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CuI-Catalyzed Alkyne–Azide “Click” Cyclo
✍ Victoria D. Bock; Henk Hiemstra; Jan H. van Maarseveen 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 414 KB

## Abstract Cu^I^‐catalyzed alkyne–azide cycloaddition provides 1,4‐disubstituted 1,2,3‐triazoles with such efficiency and scope that the transformation has been described as “click” chemistry. An overview of the mechanism of this remarkable reaction is presented as a means to explain the myriad of