CuI-Catalyzed Alkyne–Azide “Click” Cyclo
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Victoria D. Bock; Henk Hiemstra; Jan H. van Maarseveen
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Article
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2006
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John Wiley and Sons
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English
⚖ 414 KB
## Abstract Cu^I^‐catalyzed alkyne–azide cycloaddition provides 1,4‐disubstituted 1,2,3‐triazoles with such efficiency and scope that the transformation has been described as “click” chemistry. An overview of the mechanism of this remarkable reaction is presented as a means to explain the myriad of