The study includes parts of the doctoral thesis of Bettina Schlehe.
Lifetime history of alcohol consumption and K-ras mutations in pancreatic ductal adenocarcinoma
✍ Scribed by Marta Crous-Bou; Miquel Porta; Tomàs López; Manel Jariod; Núria Malats; Eva Morales; Luisa Guarner; Juli Rifà; Alfredo Carrato; Francisco X. Real
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 116 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.20483
No coin nor oath required. For personal study only.
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## Background: The authors sought to elucidate the histogenesis of pancreatic ductal carcinoma by correlating k-ras mutation with mucus type in normal epithelium, mucous cell hyperplasia (mch), and carcinoma. ## Methods: Seventy-four solid-type carcinomas (scs), 23 ductectatic-type carcinomas (dc
The aims of this study were (i) to assess the prevalence and spectrum of codon 12 Ki-ras mutations in patients diagnosed with exocrine pancreatic cancer (EPC) in 2 general hospitals between 1980 and 1990, (ii) to analyze the association of this genetic alteration with clinical and pathological chara
## Abstract Intraductal papillary‐mucinous tumors (IPMT) consist of cells with varying histologic degrees of severity and exhibit multiple tumor loci; however, whether or not these lesions exhibit the same genetic changes has not been clarified. To investigate this point, we analyzed K‐ras mutation