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Life-or-death decisions by the Bcl-2 protein family

โœ Scribed by Jerry M Adams; Suzanne Cory


Book ID
114326827
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
71 KB
Volume
26
Category
Article
ISSN
0968-0004

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## Abstract An increase in the permeability of the outer mitochondrial membrane is central to apoptotic cell death, since it leads to the release of several apoptogenic factors, such as cytochrome c and Smac/Diablo, into the cytoplasm that activate downstream death programs. During apoptosis, the m