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The BCL-2 protein family: opposing activities that mediate cell death

โœ Scribed by Youle, Richard J.; Strasser, Andreas


Book ID
109958882
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
930 KB
Volume
9
Category
Article
ISSN
1471-0072

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## Abstract An increase in the permeability of the outer mitochondrial membrane is central to apoptotic cell death, since it leads to the release of several apoptogenic factors, such as cytochrome c and Smac/Diablo, into the cytoplasm that activate downstream death programs. During apoptosis, the m