Thrombotic and hemorrhagic disorders are common complications of the myeloproliferative disorders. Endothelial cells release both procoagulant and profibrinolytic factors, which may contribute to these hemorrhagic or thrombotic complications. The pre-and postvenous stasis levels of the procoagulant
Life expectancy of patients with chronic nonleukemic myeloproliferative disorders
✍ Scribed by Ciril Rozman; Evarist Feliu; Manuel Giralt; Daniel Rubio; María-Teresa Cortés
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 594 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0008-543X
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## Abstract We report an unusual hyperdiploid karyotype characterized by the simultaneous occurrence of tetrasomy 21 and trisomy 8 detected during early blastic evolution of a BCR‐ABL‐negative chronic myeloproliferative disorder. Blast cells from this patient showed a striking response to all‐trans