Synthesis and enantioselectivity of the
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M. Novella Romanelli; Alessandro Bartolini; Carlo Bertucci; Silvia Dei; Carla Gh
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Article
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1996
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John Wiley and Sons
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English
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The enantiomers of two a-tropanyl esters, SM,, (1) and PG, (2), derived from (+)-R-hyoscyamine, that act by increasing the central cholinergic tone, were obtained by esterification after resolution of the corresponding racemic acids [(-)-S-1, (-)-R-2 and(+)-S-2] and by stereospecific synthesis [(+)-