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Lewy-like pathology in mice transgenic for mutant (A53T) human α-synuclein

✍ Scribed by Bernd Sommer; Herman van der Putten; Karl-Heinz Wiederhold; Samuel Barbieri; Graeme Bilbe


Book ID
117411544
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
187 KB
Volume
21
Category
Article
ISSN
0197-4580

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## Abstract Genetic mutations associated with α‐synuclein (α‐Syn) are implicated in the pathogenesis of Parkinson's disease (PD). PD is primarily a movement disorder, but patients are known to experience anxiety and other mood disorders. In this study, we examined the effect of the hA53T mutation d