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Lewy body pathology is associated with mitochondrial DNA damage in Parkinson's disease

✍ Scribed by Müller, Sarina K.; Bender, Andreas; Laub, Christoph; Högen, Tobias; Schlaudraff, Falk; Liss, Birgit; Klopstock, Thomas; Elstner, Matthias

Book ID
120240165
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
174 KB
Volume
34
Category
Article
ISSN
0197-4580

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✍ N. P. Quinn; P. Luthert; M. Honavar; C. D. Marsden 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 390 KB

The case of a patient with levodopa-responsive pure akinesia and freezing of gait for 17 years, whose brain showed the classical changes of Lewy body Parkinson's disease at postmortem is presented. A short trial of DLthreo-DOPS was ineffective. Intellectual function was preserved despite the presenc