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Lewis Acid-Mediated Generation of Bicyclo[5.3.0]decanes and Bicyclo[4.3.0]nonanes

โœ Scribed by Deak, Holly L.; Williams, Michael J.; Snapper, Marc L.


Book ID
126146612
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
93 KB
Volume
7
Category
Article
ISSN
1523-7060

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1,2 Disubstituted methylenecyclopropyl bromides, 6 and 11, undergo radical cascade reactions, involving cyclisation, ring-opening and further cyclisation, to give cis bicyclic products in 67% and 41% yields respectively.