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LEVODOPA TREATMENT MAY BENEFIT OR IMPAIR "FRONTAL" FUNCTION IN PARKINSON'S DISEASE

✍ Scribed by Gotham, A.-M.; Brown, R.G.; Marsden, C.D.

Book ID: 121946293
Publisher: The Lancet
Year: 1986
Tongue: English
Weight: 296 KB
Volume: 328
Category: Article
ISSN: 0140-6736
DOI: 10.1016/S0140-6736(86)90617-3

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## Abstract Long‐term treatment of human Parkinson's disease with levodopa or dopamine agonists is often complicated by the appearance of abnormal involuntary movements (dyskinesias) that are extremely difficult to control. Little is known of the cause, pathophysiological mechanisms, or possible st