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Levodopa stability in solution: Time course, environmental effects, and practical recommendations for clinical use

โœ Scribed by Dr. Eric J. Pappert; Colleen Buhrfiend; Jack W. Lipton; Paul M. Carvey; Glenn T. Stebbins; Christopher G. Goetz


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
252 KB
Volume
11
Category
Article
ISSN
0885-3185

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Levodopa stability in solution: Time cou
โœ Dr. Eric J. Pappert; Colleen Buhrfiend; Jack W. Lipton; Paul M. Carvey; Glenn T. ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 252 KB

We defined the temporal stability characteristics of levodopdcarbidopa (LD/CD) solution, and determined the effects of temperature, ascorbate, and light on LD stability over 7 days. At room temperature and without ascorbate, LD levels significantly declined by 48 h. Ascorbate prolonged stability to