The effects of cold acclimation on the activity levels of creatine kinase, lactate dehydrogenase and lactate dehydrogenase isoenzymes in various tissues/ organs of the rat (Rattus norvegicus) were investigated. Male Sprague-Dawley rats were divided into two groups. One group was housed at 4+/-1 degr
Levels of lactate dehydrogenase and creatine kinase in plasma of fluoride-treated rabbits
✍ Scribed by M. Nedeljković; V. Matović; D. Soldatović
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 264 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0260-437X
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✦ Synopsis
The effect of different concentrations of fluoride (as sodium fluoride) on the enzymes lactate dehydrogenase (LDH, EC 1.1.1.27) and creatine kinase (CK, EC 2.7.3.2) in rabbit plasma was investigated in vivo and in vitro. Rabbits were dosed orally, for 30 days, with fluoride at 2, 10 or 20 mg per kg body weight as sodium fluoride. LDH and CK levels were determined at lO-day intervals during the treatment. Fluoride, depending on the apphed dose, inhibited, had no effect or stimulated the rnvestigatea enzymes in vivo. On the other hand, fluoride had no effect on the activity of LDH and CK in vitro.
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