The protective effect of melatonin, 6-hydroxymelatonin and N-acetylserotonin against alpha-naphthylisothiocyanate (ANIT)-induced liver injury was investigated and compared in rats injected once with the hepatotoxicant (75 mg/kg body weight). In rats injected with ANIT alone, liver injury with choles
Leukotrienes and α-naphthylisothiocyanate-induced liver injury
✍ Scribed by Marc B. Bailie; Lawrence J. Dahm; Marc Peters-Golden; Richard R. Harris; George W. Carter; Robert A. Roth
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 776 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0300-483X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## HEPATOLOGY Copyright (C 19% by the American Asscx.iati(in for the Studv ol Imer Diseases
Uptake, metabolism and biliary elimination of infused cysteinyl leukotrienes were investigated in single-pass perfused rat liver. Hypoxia did not impair uptake of infused [3H]leukotriene C4, but inhibited biliary excretion of radioactivity by about 50% compared with normoxic control experiments. In
We read with interest the excellent article by Ioannou and colleagues demonstrating that diet may be an important determinant of liver disease, after adjusting for potential confounders including daily consumption of protein, carbohydrates, alcohol, fat, tea, and coffee; as well as sex, body mass in