Leukotriene B4 in bile and culture supernatant of kupffer cells in rat
β Scribed by Yoshihide Sakagami; Yasuhiro Mizoguchi; Norifumi Kawada; Shuichi Seki; Kenzo Kobayashi; Seiji Morisawa
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 51 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0192-0561
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## Abstract We previously proposed that an enzymatic cooperation between Kupffer cells and hepatocytes may play an important role in cysteinyl leukotriene (LT) production in rat liver. An__in vitro__transcellular synthesis cysteinyl LTs by a Kupffer cellβhepatocyte coculture system was characterize
Analysis by gas chromatography/mass spectrometry (GC/MS) of derivatized metabolites formed following incubation of leukotriene B, (LTB,) incubation with Ito cells extends previous knowledge concerning fragmentation mechanisms for derivatized hydroxy-substituted unsaturated fatty acids. LTB, was meta
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