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Leucine-rich repeat kinase 2 mutants I2020T and G2019S exhibit altered kinase inhibitor sensitivity

✍ Scribed by Laurie J. Reichling; Steven M. Riddle


Book ID
116298568
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
339 KB
Volume
384
Category
Article
ISSN
0006-291X

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## Abstract The behavioral and cognitive features of the leucine‐rich repeat kinase G2019S mutation in Parkinson's disease in the Ashkenazi Jewish population are not well described; therefore, we sought to more systematically characterize these features using a semistructured psychiatric interview