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Leucine-rich repeat kinase 1: a paralog ofLRRK2and a candidate gene for Parkinson’s disease

✍ Scribed by Julie P. Taylor; Mary M. Hulihan; Jennifer M. Kachergus; Heather L. Melrose; Sarah J. Lincoln; Kelly M. Hinkle; Jeremy T. Stone; Owen A. Ross; Robert Hauser; Jan Aasly; Thomas Gasser; Haydeh Payami; Zbigniew K. Wszolek; Matthew J. Farrer


Book ID
106257173
Publisher
Springer
Year
2007
Tongue
English
Weight
234 KB
Volume
8
Category
Article
ISSN
1364-6745

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Leucine-rich repeat kinase 2 (LRRK2): A
✍ Payal N. Gandhi; Shu G. Chen; Amy L. Wilson-Delfosse 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB

## Abstract Parkinson's disease (PD) is the most common neurodegenerative movement disorder, with a prevalence of more than 1% after the age of 65 years. Mutations in the gene encoding leucine‐rich repeat kinase‐2 (__LRRK2__) have recently been linked to autosomal dominant, late‐onset PD that is cl