Letter to the editor: Tropisetron in the prevention of nausea and vomiting in 131 children receiving cytotoxic chemotherapy

✍ Scribed by Berberoglu, Semha

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 10 KB
• Volume: 28
• Category: Article
• ISSN: 0098-1532
• DOI: 10.1002/(sici)1096-911x(199703)28:3<241::aid-mpo20>3.0.co;2-g

✦ Synopsis

Tropisetron in the Prevention of Nausea and Vomiting in 131 Children Receiving Cytotoxic Chemotherapy I have read with interest the report by Benoit et al. [1] were two infants. I agree with the authors that the efficacy and safety data was similar to those reported for older concerning the efficacy of tropisetron in the prevention of nausea and vomiting in children receiving cytotoxic children. chemotherapy, which appeared in the last issue of the journal. Semha Berberoglu, MD Department of Pediatric Oncology In a recent study [2], I have also evaluated the antiemetic efficacy of tropisetron in 15 children with malig-Oncology Hospital Mesa Koru Sitesi nant disease who have received cisplatin (CDDP) either alone (1/15) or in combination (14/15) with other highly Sedir Sok. 2/c 06798 Ankara, Turkey emetogenic cytotoxic drugs (Table 1). The dose of CDDP ranged between 80-120 mg/m2/day. The administration REFERENCES of tropisetron, dosage and the grading scale used were same as the authors' study. Patients were followed for 5 1. Benoit Y, Hulstaert F, Vermylen C, Sariban E, Hoyoux C, Uytte- days. Complete control on day 1 was obtained in 53.3% broeck A, Otten J, Laureys G, De Kerpel I, Nortier D, Ritter L, Keyser P: Tropisetron in the prevention of nausea and vomiting