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Letter to the editor: “Outcome of post-radiation secondary glioblastoma in children”

✍ Scribed by Stragliotto, Giuseppe; Packer, Roger J.; Rausen, Aaron R.; Coccia, Peter F.; Meadows, Anna T.; Phillips, Peter C.; Finlay, Jonathan L.

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
136 KB
Volume
30
Category
Article
ISSN
0098-1532

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✦ Synopsis

In our case report on page 360, it is erroneously stated that we used ''Human interferon ␣-2a . . . as a sterile solution for subcutaneous injection . . . .'' It should have read: ''Human interferon ␣-2a . . . as the lyophilized powder (also containing sodium chloride and albumin), and reconstituted with normal saline . . . .''

We regret the error, and believe it is important to make the point that we have always used the desiccated, sterile powder rather than the dissolved product, which is for-mulated with alcohol. The ready-to-use solution has been implicated in the neurotoxicity seen in some infants with hemangiomas treated with interferon.

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