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Lethality of hydrogen peroxide in wild type and superoxide dismutase mutants of Escherichia coli. (A hypothesis on the mechanism of H2O2-induced inactivation of Escherichia coli)

✍ Scribed by O. Cantoni; G. Brandi; G.F. Schiavano; A. Albano; F. Cattabeni


Book ID
113137210
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
427 KB
Volume
70
Category
Article
ISSN
0009-2797

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## Abstract **Background:** We recently found that the Escherichia coli Orf135 protein, a MutT‐type enzyme, hydrolysed 2‐hydroxy‐dATP (2‐OH‐dATP), and less efficiently, 8‐hydroxy‐dGTP. **Results:** In this study, we examined the effects of the absence of the orf135 gene. Frequencies of spontaneous