Lethal effects of cocaine are reduced by the dopamine-1 receptor antagonist SCH 23390 but not by haloperidol
β Scribed by Jeffrey M. Witkin; Steven R. Goldberg; Jonathan L. Katz
- Book ID
- 118343781
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 375 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0024-3205
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
This study examined the effects of both systemic and intraaccumbens administration of SCH-23390 in rats on dopamine D1 receptor occupancy and on locomotor activity produced by intraaccumbens infusion of cocaine. In experiment 1, rats received SCH-23390 (0-1 mg/kg, IP) 15 minutes prior to intraaccumb
Dopamine D 1 -receptor binding in the basal ganglia is differentially regulated by subtype nonspecific dopamine antagonists such as the antipsychotic, Fluphenazine. The purpose of the present study was to determine the relative contributions of D 1 and D 2 receptor systems in the regulation of basal