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Let-7 microRNA regulates p53 and K-ras in colorectal cancer cells

✍ Scribed by Marjun Philip Narciso Duldulao; Wendy Lee; Maithao Le; Zhenbin Chen; Wenyan Li; Joseph Kim; Julio Garcia-Aguilar

Book ID
113680571
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
88 KB
Volume
213
Category
Article
ISSN
1072-7515

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## Abstract Gene mutations in __APC__, __K‐ras__, and __p53__ are thought to be essential events for colorectal cancer development. Recent data seem to indicate that __K‐ras__ and __p53__ mutations rarely co‐exist in the same tumor, indicating that these alterations do not represent a synergistic e