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Leptin secretion rate increases with higher CAG repeat number in Huntington’s disease patients

✍ Scribed by N. Ahmad Aziz; Hanno Pijl; Marijke Frölich; A.W. Maurits van der Graaf; Ferdinand Roelfsema; Raymund A.C. Roos

Book ID
108704529
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
142 KB
Volume
73
Category
Article
ISSN
0300-0664

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Huntington's disease (HD) is a neurodegenerative and hereditary disease characterized by progressive movement disorders and mental and behavioral abnormalities. The HD gene is an expanding and unstable trinucleotide repeat (CAG repeat sequences). We studied 77 individuals from 38 families with HD in