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Leptin regulates sugar and amino acids transport in the human intestinal cell line Caco-2

✍ Scribed by C. Fanjul; J. Barrenetxe; C. Iñigo; Y. Sakar; R. Ducroc; A. Barber; M. P. Lostao

Book ID
114870948
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
292 KB
Volume
205
Category
Article
ISSN
1748-1708

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The transport of 10 amino acid ester prodrugs of levovirin (LVV) was investigated in the human intestinal Caco-2 cell line in order to overcome the poor oral bioavailability of LVV, an investigational drug for the treatment of hepatitis C infection. The prodrugs were designed to improve the permeabi