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Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: reciprocal involvement of PKC-α and PPAR expression

✍ Scribed by Mie Okumura; Mayumi Yamamoto; Hiroya Sakuma; Toshihiro Kojima; Takako Maruyama; Marjan Jamali; Denise R Cooper; Keigo Yasuda


Book ID
114150249
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
467 KB
Volume
1592
Category
Article
ISSN
0167-4889

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## Glucose concentration may be an important factor in breast cancer cell proliferation because the prevalence of breast cancer is high in diabetic patients. To determine the role of protein kinase C (PKC)-␤II in regulating MCF-7 cell proliferation at different glucose concentrations, the effects o