Lepirudin as a safe alternative for effective anticoagulation in patients with known heparin-induced thrombocytopenia undergoing percutaneous coronary intervention: Case reports

Report of successful use of argatroban a

Report of successful use of argatroban as an alternative anticoagulant during coronary stent implantation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome

✍ Lewis, Bruce E. ;Iaffaldano, Robert ;McKiernan, Thomas L. ;Rao, Luxman ;Donkin, 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB 👁 2 views

Heparin-induced thrombocytopenia and thrombosis syndrome (HITTS) is a severe complication of heparin caused by an antibody response to the heparin-platelet factor 4 complex which results in severe thrombosis. Heparin rechallenge in HllTS patients carries a high risk of inducing thrombosis. Antithrom