✦ LIBER ✦

Lentiviruses as gene delivery vectors

✍ Scribed by Maurizio Federico

Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 89 KB
Volume: 10
Category: Article
ISSN: 0958-1669
DOI: 10.1016/s0958-1669(99)00008-7

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✦ Synopsis

Lentivirus vectors are already used as effective gene delivery tools in cells from liver, retina, skeletal muscle and the central nervous system. In the past year, new and exciting data from gene transfer experiments in human hematopoietic progenitor cells have been obtained. Furthermore, new generations of HIV-1 based lentivirus vectors as well as new potentially less pathogenic HIV-2 based vectors have been described; however, old and new obstacles remain to be cleared.

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