A Class of Cationic Triblock Amphiphilic Oligopeptides as Efficient Gene-Delivery Vectors
✍ Scribed by Wei Yang Seow; Yi-Yan Yang
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 315 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0935-9648
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📜 SIMILAR VOLUMES
Cholesterol-conjugated H 5 R 10 and H 10 R 10 oligopeptides (HR15-Chol and HR20-Chol) were designed and synthesized. These amphiphilic oligopeptides were able to self-assemble into cationic micelles in aqueous solution at low concentrations, and their critical micelle concentrations in sodium acetat
## Abstract In this study, ABC‐type triblock copolymers, poly(ethylene glycol)‐__b__‐poly(ε‐caprolactone)‐__b__‐poly(2‐(2‐aminoethyl amino) ethyl methacrylate)s (PEG‐PCL‐PAEAEMAs), composed of novel poly(2‐(2‐aminoethyl amino) ethyl methacrylate) (PAEAEMA) that have a primary and a secondary amino