An optimized amphiphilic cationic peptide as an efficient non-viral gene delivery vector
✍ Scribed by Jesús Fominaya; María Gasset; Rosana García; Fernando Roncal; Juan Pablo Albar; Antonio Bernad
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 242 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1099-498X
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📜 SIMILAR VOLUMES
Cholesterol-conjugated H 5 R 10 and H 10 R 10 oligopeptides (HR15-Chol and HR20-Chol) were designed and synthesized. These amphiphilic oligopeptides were able to self-assemble into cationic micelles in aqueous solution at low concentrations, and their critical micelle concentrations in sodium acetat
## Abstract Viral‐mediated gene delivery has been explored for the treatment and protection of cardiomyocytes, but so far there is only one report using cationic polymer for gene delivery to cardiomyocytes in spite of many advantages of polymer‐mediated gene delivery. In this study, a cationic poly