## Abstract ## Background For many applications, efficient gene therapy will require long‐term, organ‐specific therapeutic gene expression. Lentiviral vectors based on HIV‐1 are promising gene delivery vehicles due to their ability to integrate transgenes into non‐dividing cells. Many experimental
✦ LIBER ✦
Lentiviral vectors with amplified β cell-specific gene expression
✍ Scribed by Shaw, K L; Pais, E; Ge, S; Hardee, C; Skelton, D; Hollis, R P; Crooks, G M; Kohn, D B
- Book ID
- 109855305
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 497 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0969-7128
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## Abstract ## Background Lentiviral vectors are attractive delivery tools for gene therapy, especially in terminally differentiated target cells. While restriction of gene expression to specific cell populations is of particular importance, highly efficient cell‐type‐specific gene expression afte