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Leflunomide induces immunosuppression in collagen-induced arthritis rats by upregulating CD4 + CD25 + regulatory T cells

✍ Scribed by Wang, Ting-Yu; Li, Jun; Li, Chang-Yu; Jin, Yong; Lü, Xiong-Wen; Wang, Xiao-Hua; Zhou, Qian

Book ID
121237098
Publisher
NRC Research Press
Year
2010
Tongue
French
Weight
305 KB
Volume
88
Category
Article
ISSN
0008-4212

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## Abstract ## Objective We previously demonstrated that CD4+,CD25+ regulatory T (Treg) cells are present in increased numbers in the synovial fluid (SF) of rheumatoid arthritis (RA) patients and display enhanced suppressive activity as compared with their peripheral blood (PB) counterparts. Despi