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Leber's optic neuropathy I. Clinical studies

✍ Scribed by A. Stehouwer; L. N. Went


Publisher
Springer-Verlag
Year
1982
Tongue
English
Weight
764 KB
Volume
53
Category
Article
ISSN
0012-4486

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This article reviews the literature on point mutation of mitochondria1 DNA (mtDNA) among Japanese and the authors' research data on pupil reaction in patients with Leber's hereditary optic neuropathy (LHON). Among Japanese, a higher frequency (80-90%) of point mutation at nucleotide position 11778 o