Laureatin, a constituent from laurencia nipponica yamada

✍ Scribed by Toshi Irie; Motowo Izawa; Etsuro Kurosawa

• Publisher: Elsevier Science
• Year: 1968
• Tongue: French
• Weight: 340 KB
• Volume: 9
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)89750-6

✦ Synopsis

We describe herein the isolation and structural elucidation of a new bromo compound, designated as laureatin, in Laurencia ninoonica Yamada (Japanese name Urasozo; Rhodomelaceae). Laureatin (I), C15H2002Br2 (Mf 394, 392 and 390), m.p. 82-83', la], +96" @X4), was isolated in 0.05% yield by chromatographic purification of the neutral fraction from methanol extracts of the dried seaweed. The UV,nEkp 223 rnp (E 12,800) and ainfl 229 (10,400), and IR spectra,3::: 3300, 2100, 1140, -1 1086, 1045, 975 and 965 cm , indicate that I is an ether having a conjugate en- yne group and contains neither hydroxyl nor carbonyl function. The NMR spectrum (2) and the spin decoupling study (Fig. 1A) confirm the presence of groups -CH2-C(H-A)=C(H-B)-CZC(H-I) (3) and -C(H-Ll)(H-L2)-C(H-M)3:23.97