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Laterally Stabilized Complexes of DNA with Linear Reducible Polycations: Strategy for Triggered Intracellular Activation of DNA Delivery Vectors

✍ Scribed by Oupický, David; Parker, Alan L.; Seymour, Leonard W.

Book ID: 120820348
Publisher: American Chemical Society
Year: 2002
Tongue: English
Weight: 43 KB
Volume: 124
Category: Article
ISSN: 0002-7863
DOI: 10.1021/ja016440n

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## Abstract **Summary:** The interaction between negatively charged lipid vesicles and positively charged DNA/polylysine complexes was studied. The interaction does not lead to release of DNA from the initial complexes. The particles formed are easy to prepare, they have slight negative charge, sma