Latent Varicella-Zoster Virus in Human Dorsal Root Ganglia
โ Scribed by Peter G.E. Kennedy; Esther Grinfeld; John W. Gow
- Book ID
- 112272607
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 147 KB
- Volume
- 258
- Category
- Article
- ISSN
- 0042-6822
No coin nor oath required. For personal study only.
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We describe here the first in vivo model of varicellazoster virus (VZV) latent infection in the adult rat peripheral nervous system. Infected Mew0 cells were injected subcutaneously along the spine of healthy adult rats. No clinical sign of infection was observed even 9 months after inoculation. Hum
Varicella-zoster virus (VZV) becomes latent in the sensory ganglia after primary infection and VZV DNA has been found in human trigeminal, thoracic, and geniculate ganglia. In this study, human vestibular and spiral ganglia, which do not received innervation from the skin, were examined for VZV DNA