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Late-onset Papillon-Lefèvre syndrome without alteration of the cathepsin C gene

✍ Scribed by Ulrike Pilger; Hans Christian Hennies; Astrid Truschnegg; Elisabeth Aberer


Book ID
117393748
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
266 KB
Volume
49
Category
Article
ISSN
1097-6787

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Papillon-Lefèvre syndrome (PLS) has recently been shown to be caused by mutations in the cathepsin C gene resulting in periodontal disease and palmoplantar keratosis. Thirteen different homozygous mutations have been characterised in PLS patients of different ethnic origin. In the present paper, a P