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Description of Two New Cathepsin C Gene Mutations in Patients With Papillon-Lefèvre Syndrome

✍ Scribed by Wani, Aijaz Ahmad; Devkar, Nihal; Patole, Milind S.; Shouche, Yogesh S.


Book ID
127029396
Publisher
American Academy of Periodontology
Year
2006
Tongue
English
Weight
185 KB
Volume
77
Category
Article
ISSN
0022-3492

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✍ Luis M. Allende; Miguel A. García-Pérez; Angel Moreno; Alfredo Corell; Miguel Ca 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 27 KB

Papillon-Lefèvre syndrome (PLS) has recently been shown to be caused by mutations in the cathepsin C gene resulting in periodontal disease and palmoplantar keratosis. Thirteen different homozygous mutations have been characterised in PLS patients of different ethnic origin. In the present paper, a P