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Late antiischaemic action of the stable PGI2 analogue: 7-oxo-PGI2

✍ Scribed by É. Udvary; L. Szekeres

Book ID
119442465
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
87 KB
Volume
19
Category
Article
ISSN
0022-2828

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Stereocontrolled synthesis of 7-hydroxy-
Stereocontrolled synthesis of 7-hydroxy- and 7-acetoxy-PGI2: New stable PGI2 analogues
✍ Kiyoshi Bannai; Takeshi Toru; Takeo Ba; Toshio Tanaka; Noriaki Okamura; Kenzo Wa 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 238 KB

Stable analogues of PGIz, 7-hydroxy-and 7-acetoxy-PGIz, were synthesized from protected PGIz methyl ester G via sulfoxides 6a, 6& through stereocontrolled sulfoxide-sulfenate rearrangement.