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Large-scale mitochondrial DNA deletion mutations and nuclear genome instability in human breast cancer

✍ Scribed by Weizhu Zhu; Wenyi Qin; Edward R. Sauter


Book ID
113524206
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
169 KB
Volume
28
Category
Article
ISSN
0361-090X

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## Abstract Mitochondrial DNA (mtDNA) large deletions and mtDNA mutations have been demonstrated in various types of human cancer. The relationship between the occurrence of such alterations and the nuclear microsatellite instability (MSI) status of the neoplastic cells remains controversial. In an