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LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer

โœ Scribed by Ong, D C T; Ho, Y M; Rudduck, C; Chin, K; Kuo, W -L; Lie, D K H; Chua, C L M; Tan, P H; Eu, K W; Seow-Choen, F


Book ID
109971068
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
797 KB
Volume
28
Category
Article
ISSN
0950-9232

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Loss of heterozygosity at 11q23.1 and su
โœ Kirsten Laake; Virpi Launonen; Dieter Niederacher; Sigfridur Gudlaugsdottir; Sus ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 237 KB ๐Ÿ‘ 2 views

Among the chromosomal regions commonly undergoing deletions in breast tumors is 11q23.1. The genes that are targets for loss of heterozygosity (LOH) in this region is not yet established. One of the candidate genes located in this region is ATM, responsible for the rare autosomal recessive disorder