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Laparoscopic oophoropexy and ovarian function in the treatment of Hodgkin disease

✍ Scribed by R. Stan Williams; Ramey D. Littell; Nancy P. Mendenhall

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 66 KB
Volume: 86
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19991115)86:10<2138::aid-cncr36>3.0.co;2-v

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✦ Synopsis

BACKGROUND.

Hodgkin disease commonly affects women of reproductive age.

Total lymph node irradiation (TNI) typically delivers a dose of 2000 -4000 centigray (cGy) to the ovaries, which invariably results in premature ovarian failure (POF) and infertility unless the ovaries are shielded. Transposition of the ovaries at staging laparotomy has had mixed success and may be remote in time from pelvic radiation.

METHODS. A laparoscopic technique has been described that allows transposition

of the ovaries just prior to pelvic radiation. This is a report of the outcome of 12 patients who underwent laparoscopic oophoropexy at the University of Florida from 1989 to 1995. Two were excluded from analysis, because one died and the other had a second malignancy for which radiation was aborted.

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