Langerhans cell histiocytosis: A reactive or neoplastic disorder?
β Scribed by Zelger, Bernhard
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 36 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0098-1532
- DOI
- 10.1002/mpo.1249
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π SIMILAR VOLUMES
A study of 47 well-documented patients with Langerhans cell histiocytosis (LCH) showed a slight female preponderance, with onset as late as the ninth decade. The skin was the commonest site of presentation, but pulmonary and bone involvement was frequent. Patients with single-site disease did best.
Background. Treatment of multisystem Langerhans cell histiocytosis (LCH) remains difficult. Various regimens of single and multiagent chemotherapy have been used, but a significant proportion of patients fail to respond to treatment. Procedure. We have evaluated the use of cyclosporine A (CSA) in a