Lamivudine resistance in patients with chronic hepatitis B: Role of clinical and virological factors
β Scribed by Alexander J V Thompson; Anna Ayres; Lilly Yuen; Angeline Bartholomeusz; D Scott Bowden; David M Iser; Robert Y M Chen; Barbara Demediuk; Gideon Shaw; Sally J Bell; Katrina J R Watson; Stephen A Locarnini; Paul V Desmond
- Book ID
- 108951102
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 181 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0815-9319
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## Abstract The aims of this study were to assess the longβterm efficacy of lamivudine (LAM) plus adefovir dipivoxil (ADV) combination therapy in patients with chronic hepatitis B resistant to LAM, to identify predictive factors of complete viral response (HBVβDNA <2.6βlogβcopies/ml at 12 months of
The effect of lamivudine treatment on the outcome of patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis is unclear. In a retrospective multicenter study, we have analyzed the virological events observed during lamivudine therapy in patients with HBeAgnegative chronic hepatitis an